Slideshows Images Quizzes
- Generic Name: phenazopyridine
- Brand Name: Pyridium
Last reviewed on RxList: 9/1/2016
PROFESSIONAL CONSUMER SIDE EFFECTS
Drug Description Indications & Dosage Side Effects & Drug Interactions Warnings & Precautions Overdosage & Contraindications Clinical Pharmacology Medication Guide
home drugs a-z list side effects drug center pyridium (phenazopyridine) drug
Find Lowest Prices on
(phenazopyridine hydrochloride) Tablets, USP
CAUTION: Federal law prohibits dispensing without prescription.
Pyridium® (Phenazopyridine Hydrochloride) is light or dark red to dark violet, odorless, slightly bitter, crystalline powder. It has a specific local analgesic effect polycitra dosing of cipro in the urinary tract, promptly relieving burning and pain. It has the following structural formula:
Pyridium (Phenazopyridine HCl Tablets, USP) contains the following inactive ingredients: carnauba wax, croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone and pregelatinized starch.
What are the possible side effects of phenazopyridine?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using phenazopyridine and call your doctor at once if you have any of these serious side effects:
- pale skin, fever, confusion or weakness;
- jaundice (yellowing of your skin or eyes);
- urinating less than usual or not at all;
- drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting;
- swelling, weight gain, feeling short of breath; or
Read All Potential Side Effects and See Pictures of Pyridium »
Indications & Dosage
Pyridium is indicated for the symptomatic relief of pain, burning, urgency, frequency, and other discomforts arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters. The use of Phenazopyridine HCl for relief of symptoms should not delay definitive diagnosis and treatment of causative conditions. Because it provides only symptomatic relief, prompt appropriate treatment of the cause of pain must be instituted and Phenazopyridine HCl should be discontinued when symptoms are controlled.
The analgesic action may reduce or eliminate the need for systemic analgesics or narcotics. It is, however, compatible with antibacterial therapy and can help to relieve pain and discomfort during the interval before antibacterial therapy controls the infection. Treatment of a urinary tract infection with Phenazopyridine HCl should not exceed two days because there is a lack of evidence that the combined administration of Phenazopyridine HCl and an antibacterial provides greater benefit than administration of the antibacterial alone after two days. (See DOSAGE AND ADMINISTRATION section.)
DOSAGE AND ADMINISTRATION
100 mg Tablets: Average adult dosage is two tablets 3 times a day after meals.
200 mg Tablets: Average adult dosage is one tablet 3 times a day after meals.
When used concomitantly with an antibacterial agent for the treatment of a urinary tract infection, the administration of Phenazopyridine HCl should not exceed 2 days.
100 mg Tablets: Supplied in bottles of 100 (NDC 60846-517-01) counts.
Appearance: Deep brown to maroon colored, round, film coated tablets debossed “AN” above “1” on one side and plain on the other.
200 mg Tablets: Supplied in bottles of 100 (NDC 60846-520-01) counts.
Appearance: Deep brown to maroon colored, round, film coated tablets debossed “AN” above “2” on one side and plain on the other.
DISPENSE contents with a child-resistant closure (as required) and in a tight container as defined in the USP.
STORE at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature].
Manufactured for: Gemini Laboratories, LLC, Bridgewater, NJ 08807. Rev. Feb 2014
Side Effects & Drug Interactions
Headache, rash, pruritus and occasional gastrointestinal disturbance. An anaphylactoid-like reaction has been described. Methemoglobinemia, hemolytic anemia, renal and hepatic toxicity have been reported, usually at overdosage levels (see OVERDOSAGE section).
No information provided.
Warnings & Precautions
No information provided.
A yellowish tinge of the skin or sclera may indicate accumulation due to impaired renal excretion and the need to discontinue therapy. The decline in renal function associated with advanced age should be kept in mind.
NOTE: Patients should be informed that Phenazopyridine HCl produces a reddish-orange discoloration of the urine and may stain fabric. Staining of contact lenses has been reported.
Laboratory Test Interaction
Due to its properties as an azo dye, Phenazopyridine HCl may interfere with urinalysis based on spectrometry or color reactions.
Carcinogenesis, Mutagenesis, Impairment Of Fertility
Long-term administration of Phenazopyridine HCl has induced neoplasia in rats (large intestine) and mice (liver). Although no association between Phenazopyridine HCl and human neoplasia has been reported, adequate epidemiological studies along these lines have not been conducted.
Pregnancy Category B
Reproduction studies have been performed in rats at doses up to 50 mg/kg/day and have revealed no evidence of impaired fertility or harm to the fetus due to Phenazopyridine HCl. There are, however, no adequate and well controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
No information is available on the appearance of Phenazopyridine HCl, or its metabolites in human milk.
Overdosage & Contraindications
Exceeding the recommended dose in patients with good renal function or administering the usual dose to patients with impaired renal function (common in elderly patients) may lead to increased serum levels and toxic reactions. Methemoglobinemia generally follows a massive, acute overdose. Methylene blue, 1 to 2 mg/kg/body weight intravenously or ascorbic acid 100 to 200 mg given orally should cause prompt reduction of the methemoglobinemia and disappearance of the cyanosis which is an aid in diagnosis. Oxidative Heinz body hemolytic anemia may also occur, and “bite cells” (degmacytes) may be present in a chronic overdosage situation. Red blood cell G-6-PD deficiency may predispose to hemolysis. Renal and hepatic impairment and occasional failure, usually due to hypersensitivity, may also occur.
Phenazopyridine HCl should not be used in patients who have previously exhibited hypersensitivity to it. The use of Phenazopyridine HCl is contraindicated in patients with renal insufficiency.
Phenazopyridine HCl is excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract. This action helps to relieve pain, burning, urgency and frequency. The precise mechanism of action is not known.
The pharmacokinetic properties of Phenazopyridine HCl have not been determined. Phenazopyridine HCl is rapidly excreted by the kidneys, with as much as 66% of an oral dose being excreted unchanged in the urine.
No information provided. Please refer to the PRECAUTIONS section.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Pyridium Drug Imprint
Phenazopyridine 100 mg-AMN
round, brown, imprinted with AN 1
Phenazopyridine 100 mg-GG
round, maroon, imprinted with A 003
Phenazopyridine 200 mg-AMN
round, brown, imprinted with AN 2
Phenazopyridine 200 mg-GG
round, maroon, imprinted with A 004
Phenazopyridine 200 mg-QUA
round, red, imprinted with 4972, V
Pyridium User Reviews
Health Solutions From Our Sponsors
RxList Home Drugs & Medications Slideshows Pill Identification Tool Vitamins, Herbs, & Dietary Supplements Images Diseases Symptom Checker Dictionary Quizzes
WebMD Medscape Medscape Reference eMedicineHealth MedicineNetOnHealth BootsWebMD Medscape France Medscape Germany
Copyright © 2017 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.
Search - Sickkids Ciprofloxacin tablet identification chart # How To Detox From Marijuana For Drug Test - Best Fat
Antibiothrapie des infections ostoarticulaires pyognes
AtroPen (atropine IV/IM) dosing, indications, interactions
Azithromycin (Zithromax) for Chlamydia Infection
CIPRO (Ciprofloxacin) dosage, indication, interactions, side
Capital Coast Resort Spa
Cipro (Ciprofloxacin Side Effects, Interactions, Warning)
Cipro 500 Mg 14 Tablet - la Prospektüsü